BCMP Summer Internship

Arthanari Laboratory  Hari's work on novel pulse sequences, pulse designs, labeling strategies, and sampling schemes let his group push the boundaries of NMR as a technique, allowing him to tackle larger systems by NMR.

Blacklow Laboratory  Focus on how other proteins genetically implicated in the Notch pathway modulate signaling in normal and cancer contexts. Priorities include understanding the molecular mechanism of normal and pathogenic activation by ADAM-family metalloproteases, elucidating how Notch cooperates with other factors to control target gene transcription and understanding how negative feedback regulators fine-tune signaling.

Eck Laboratory  Focus on the biochemical and biophysical methods (including X-ray crystallography and cryo electron microscopy) to distill problems of central importance in cancer biology to their structural and mechanistic essentials; especially interested in the structure and regulation of kinases and their mutational activation in cancer, and in using structural approaches to facilitate development of anti-cancer drugs.